Improve health with personalized solutions



Cancer treatments are improving as scientists find ways to develop new techniques and treatments. One of them is precision medicine, where they have focused on improving the health of patients using personalized solutions.

RELATED: Oxford Genomics Pushing the Boundaries of Personalized Medicine

What is precision medicine?

Precision medicine, in its simplest definition, is how a patient is treated, diagnosed, or prevented from a disease by checking their genetics, environment, or lifestyle.

This type of treatment is linked to pharmacogenomics. When pharmacogenomics is the study of how a person’s gene affects their response to a drug, it is used to treat a person with effective and safe drugs tailored to their genes.

When is precision medicine used?

Precision medicine is now commonly used in patients being treated for pancreatic cancer, lung cancer, melanoma / skin cancer, and colon cancer. It is also used to detect and treat HIV and cystic fibrosis.

Slowly, it is also observed in the treatments of heart disease, Alzheimer’s disease, rheumatoid arthritis and multiple sclerosis.

In cancer patients, most medical institutions treat each patient the same. However, studies suggest that not everyone responds to treatments the same. A person’s body may respond to drugs differently than another person.

Genetics play a role in treating tumors, and precision medicine promises to tailor treatments based on a person’s genes. It’s seeing how a tumor would respond to certain treatments that might work for other people.

How is precision medicine used?

medical scanner |  Precision medicine

Precision medicine can be used in disease prevention and prediction, and management and treatment. Here are some examples of how it is used to treat, prevent, or treat people in a practical setting.

1. Family history

Checking your family’s history of illnesses and illnesses can in some way determine what you are capable of acquiring. If a family member has a history of cancer, heart disease, diabetes, high blood pressure, or other chronic illnesses, there’s a good chance you have it.

With this data and information, a doctor can create treatment plans to prevent this from happening to you.

For example, when the doctor finds out that someone in your family has had breast cancer, there’s a good chance you have it. The doctor will then decide that you have regular mammograms to check for any signs.

2. Newborn screening

Newborns (usually just after conception) are examined for blood samples. This test will check if they have any pre-existing conditions acquired from their parents, check for hearing abilities or heart defects, among other things.

This way, the baby will be treated accordingly if critical or life-threatening conditions are observed.

For example, newborn screening shows Baby Mary suffers from Severe Combined Immune Deficiency (SCID), she will immediately receive a bone marrow transplant to fight her disease. SCID puts babies’ lives at risk because it is responsible for fighting infections.

3. Personal trackers

Personal trackers such as smartwatches or other mobile devices that check your health can save your life and be tools for precision medicine.

For example, a person is told by their smart device that they have abnormal heart rates even though they have no family history of heart disease. He then goes to see a doctor because of this and was diagnosed with atrial fibrillation. This device could have saved his life as this condition can lead to a stroke. Now he can treat his condition before it gets worse.

4. Genomic sequencing

Genomic sequencing can be used to control and track infectious diseases. Similar to what has been used to track COVID-19, this approach shows the DNA of a germ or virus where scientists have the opportunity to find out more about it and find a cure to cure it. .

An example of this is COVID-19, where scientists were able to extract samples from people infected with the virus and learn more about it and find vaccines and cures, which is slowly happening to us now.

5. Tumor profiling

As a treatment, tumor profiling is a genetic test of a tumor. It is a way for doctors to choose the type of treatment they would use for a disease. They would know through this process if the cancer will come back or if it needs radiation or chemotherapy.

For example, Jenny’s breast cancer has come back and is diagnosed again. But her tumor profile reveals that she has triple negative breast cancer. His approach in this regard, as well as that of his doctors, is more aggressive, including chemotherapy, radiation therapy and mastectomy.

RELATED: FDA Approves GSK’s Jemperli Checkpoint Inhibitor for Endometrial Cancer

6. Pharmacogenomics

As mentioned above, pharmacogenomics studies how a person responds to a certain treatment based on their genes. Doctors who use this treatment can assess whether or not a certain drug may be effective based on a patient’s history. They can also determine if the patient will experience any serious side effects.

For example, John has to undergo Fluorouracil (5-FU), which is a type of chemotherapy. But if John has a low level of an enzyme called dihydropyrimidine dehydrogenase (DPD), which helps metabolize fluorouracil in the body, doctors should control it using pharmacogenomics. If he has a low dose of fluorouracil, an oncologist will decrease the dosage of chemotherapy to avoid any serious side effects.

Which companies provide this service?

These examples being revealed, certain establishments and companies offer precision medicine to improve the living conditions of patients treated for various diseases.

1. ExactCure

ExactCure is a French start-up that combines artificial intelligence and precision medicine to create flawless software for the use of drugs to be used by patients according to their kidney condition, genotype, gender or age. .

Patients use this service by entering their data, and ExactCure will provide the necessary medications based on the information provided.

2. Tepthera

Tepthera is a Swiss start-up that focuses on immunotherapy for cancer, infectious and autoimmune diseases.

Their goal in precision medicine is to identify T cell antigens for better and personalized therapies and treatments.

3. Caris Life Sciences

Caris Life Sciences is a molecular science company focused on precision medicine in oncology. They work on the development of innovative therapies and advance potential cancer treatments in the clinic.

They are developing profiling tests for oncology that analyze DNA, RNA and proteins to reveal a molecular pattern to help doctors determine the best treatment for cancer patients.

4. Precigene

Precigen is a Maryland-based company that is advancing its UltraCAR-T cell therapy approach to treating cancer.

They are now developing next-generation gene and cell therapies that can change the treatment paradigm in immuno-oncology, autoimmune diseases and infectious diseases.

There are many ways to treat illnesses and medical conditions with the use of precision medicine. Scientists are continually finding ways to improve the lives of patients using their traits.


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